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Genetically Modified Super Smart Rats.


Hobbie-J is the newest addition to creatures that have been made "super intelligent" through genetic modifications. Scientists were able to cause over-expression of the NR2B gene which increases the rate at which neurons communicate. (The article doesn't go into much more detail than that, unfortunately).

I'm curious to know if the increased neuronal communication is seen brain-wide or just in the areas that deal with spatial memory. I'm also curious if there is any detriment to brain activity in other areas while the increased memory task is being performed.

Imagine having some sort of super-association power - never forgetting directions, names, your last 5 meals, etc. The question is: Do we really want to remember everything?

Personally I can live without remembering when Becky came back on Roseanne.
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Posted By: Dylan
11/15/09 11:51 PM

Just click the link - my summary makes no sense and I am so tired I don't care anymore. Must be an NR2B deficiency.
Posted By: Virginia
11/16/09 08:31 PM

From my understanding it would be in specific areas. The brain is highly specialized so I would imagine that the additional neuronal communication would be localized as well. The brain develops with billions and billions of neurons that eventually die off very early on in life also known as neural proliferation. The neurons begin by spreading out into the brain building upon each other and as experience occurs clusters of neurons become primed and these neurons that are continually used will live and those that do not die off. As we learn and grow are brain compartmentalizes that information so you might expect these increased rates of neural connections would have to be constrained to the areas as well.

As a evolutionists I consider the entire brain, as seen in modern humans, to have slowly emerged over billions and billions of years gradually growing from very simple modules to much more advanced forms. The increased complexity resulted from a slowly building of specialized areas that evolved to solve a specific function. A common, but I believe incomplete example, of this is thinking of our brain as a Swiss army knife. Each tool was "designed" to solve a specific problem.

The paper fails to mention what they mean when saying increased neural communication so I am going to assume they might be referring to increased myelination, which is basically the insulator for the axon that conducts electrical impulses. Lack of myelination drastically can retard neuron communication, it takes much longer for the electricity to travel in the axon. Many intelligence researchers attribute individual differences in general intelligence to amounts of myelination.

I would love to not only be able to increase my general knowledge but more importantly to also maintain the integrity of my memories in old age.... that to me would be the best result form this research.

Posted By: Michael
11/17/09 12:18 AM

this is ridiculous. i havent even had my last 5 meals yet. how could i remember them. pseudoscience.